Objective: To probe into the risk factors for bronchopulmonary dysplasia (BPD) complicated with pulmonary hypertension (PH) in preterm infants. Methods: Clinical data of 202 children with BPD were retrospectively analyzed

all children were divided into the PH group (n=79) and the non-PH group (n=123) according to whether BPD was complicated with PH. Univariate and multivariate Logistic regression analysis was used to summarize the risk factors of BPD complicated with PH. Results: Univariate analysis showed that there were statistically significant differences between two groups in small gestational age (SGA)

respiratory distress syndrome (RDS)

haemodynamieally significant patent duetus arteriosus (hsPDA)

sepsis

moderate to severe BPD

invasive ventilation ≥7 d and other indicators (P<0.05). Multivariate analysis showed that RDS and hsPDA were independent risk factors for BPD complicated with PH. Conclusion: RDS and hsPDA are independent risk factors for BPD complicated with PH. For children with BPD

clinical risk factors should be identified early

timely intervention should be made to reduce the risks of BPD complicated with PH.